PF3D7_0100700

Genome location: Pf3D7_01_v3:56,690..56,893(-)

Genome classification: SubtelomericHypervariable

Function and Localization

Product Description: Plasmodium exported protein, unknown function, fragment

SignalP Peptide: N/A

# Transmembrane Domains: 0

EC Numbers: None

Curated GO (PlasmoDB): None

Expression by stage (LR - Le Roch et al., and MCA - Malaria Cell Atlas):

Stage	LR class	MCA mean	MCA prop. zeros
Sporozoite	not expressed	N/A	N/A
Ring	not expressed	nd	1.00
Trophozoite	not expressed	0.00	1.00
Schizont	not expressed	nd	1.00
Gametocyte	not expressed	nd	1.00

More info:

Resistome Mutations

Old (Pf3D7v3) Gene ID: PF3D7_0100700

Resistome Missense Mutations: None

Resistome Compounds with Missense Mutations: None

Resistome # Samples with Disruptive Mutations: 0 (0 missense, 0 "interesting" missense)

Essentiality (ABS)

Zhang Phenotype: Non - Mutable in CDS *tentative

MIS: 0.122 | MFS: 0 | #Insertions: 0

PlasmoGEM Phenotype: N/A

RMgmDB ABS Phenotype: N/A

More info: PhenoPlasm Link

Binding Evidence

AlphaFill Uniprot ID: N/A

"Best" AlphaFill ligand hit: No AlphaFill hits

No associated EC numbers

No evidence of orthology to BindingDB entries

Orthology Information

Ortholog Group (OrthoMCL): OG6_110760

No human ortholog(s)

Genetic Variation

MalariaGEN Pf7 (worldwide samples) # unique SNV/indels:

No passing variants found

PlasmoDB Total SNPs: 49

Non-coding: 1 | Synonymous: 24 | Nonsynonymous: 20 | Stop Codon: 4

Protein Information

Protein Length: 67 | Molecular Weight (kDa): 7.948

UniProt ID(s): None

PDB ID(s): None

Isoelectric Point: 6.71

Protein Domain Annotations:

Source	Family ID	Description
InterPro	IPR019111	Plasmodium RESA, N-terminal
PFam	PF09687	Plasmodium RESA, N-terminal
Superfamily	N/A	N/A