PF3D7_0114750

Genome location: Pf3D7_01_v3:566,515..566,691(-)

Genome classification: Core

Function and Localization

Product Description: Plasmodium exported protein, unknown function, fragment

SignalP Peptide: N/A

# Transmembrane Domains: 0

EC Numbers: None

Curated GO (PlasmoDB): None

Expression by stage (LR - Le Roch et al., and MCA - Malaria Cell Atlas):

Stage	LR class	MCA mean	MCA prop. zeros
Sporozoite	no data	N/A	N/A
Ring	no data	nd	nd
Trophozoite	no data	nd	nd
Schizont	no data	nd	nd
Gametocyte	no data	nd	nd

More info:

Resistome Mutations

No corresponding Pf3D7v3 gene ID in resistome database

Essentiality (ABS)

Zhang Phenotype: N/A

PlasmoGEM Phenotype: N/A

RMgmDB ABS Phenotype: N/A

More info: PhenoPlasm Link

Binding Evidence

AlphaFill Uniprot ID: A0A5K1K8N8

"Best" AlphaFill ligand hit: No AlphaFill hits

No associated EC numbers

No evidence of orthology to BindingDB entries

Orthology Information

Ortholog Group (OrthoMCL): OG6_110760

No human ortholog(s)

Genetic Variation

MalariaGEN Pf7 (worldwide samples) # unique SNV/indels:

Homozygous genotype calls only

variant type	common	rare	doubleton	singleton
synonymous	0	0	2	2
disruptive	1	7	7	9
missense	1	6	6	6

Any inclusion in genotype call

variant type	common	rare	doubleton	singleton
synonymous	2	0	2	3
disruptive	4	15	7	10
missense	3	13	3	5

PlasmoDB Total SNPs: 15

Non-coding: 0 | Synonymous: 15 | Nonsynonymous: 0 | Stop Codon: 0

Protein Information

Protein Length: 58 | Molecular Weight (kDa): 7.225

UniProt ID(s): A0A5K1K8N8

PDB ID(s): None

Isoelectric Point: 9.84

Protein Domain Annotations:

Source	Family ID	Description
InterPro	N/A	N/A
PFam	N/A	N/A
Superfamily	N/A	N/A