PF3D7_0205700

Genome location: Pf3D7_02_v3:230,768..232,631(+)

Genome classification: Core

Function and Localization

Product Description: RNA-binding protein, putative

SignalP Peptide: N/A

# Transmembrane Domains: 0

EC Numbers: None

Curated GO (PlasmoDB): None

Expression by stage (LR - Le Roch et al., and MCA - Malaria Cell Atlas):

More info:

• Malaria Parasite Metabolic Pathways (MPMP) Link
• BiGG Metabolic Model Link
• STRING Interaction Network Link

Resistome Mutations

Old (Pf3D7v3) Gene ID: PF3D7_0205700.2

Resistome Missense Mutations: None

Resistome Compounds with Missense Mutations: None

Resistome # Samples with Disruptive Mutations: 0 (0 missense, 0 "interesting" missense)

Essentiality (ABS)

Zhang Phenotype: Mutable in CDS

MIS: 0.298 | MFS: -3.275 | #Insertions: 1

PlasmoGEM Phenotype: Dispensable (Pb ortholog: PBANKA_0303400)

• Relative Growth Rate: 0.88 ± 0.22
• Confidence: 4.39

RMgmDB ABS Phenotype: Different from wild type (Pb ortholog: PBANKA_0303400)

Modification: Disrupted | RMgm-4203

More info: PhenoPlasm Link

Binding Evidence

AlphaFill Uniprot ID: O96152

"Best" AlphaFill ligand hit: No AlphaFill hits

No evidence of orthology to BindingDB entries

Orthology Information

Ortholog Group (OrthoMCL): OG6_533294

No human ortholog(s)

Genetic Variation

MalariaGEN Pf7 (worldwide samples) # unique SNV/indels:

Homozygous genotype calls only

Any inclusion in genotype call

PlasmoDB Total SNPs: 81

Non-coding: 76 | Synonymous: 4 | Nonsynonymous: 1 | Stop Codon: 0

Protein Information

Protein Length: 205 | Molecular Weight (kDa): 24.326

UniProt ID(s): O96152

PDB ID(s): None

Isoelectric Point: 7.29

Protein Domain Annotations: