PF3D7_0300600

Genome location: Pf3D7_03_v3:58,307..58,519(-)

Genome classification: SubtelomericHypervariable

Function and Localization

Product Description: Plasmodium exported protein, unknown function, fragment

SignalP Peptide: N/A

# Transmembrane Domains: 0

EC Numbers: None

Curated GO (PlasmoDB): None

Expression by stage (LR - Le Roch et al., and MCA - Malaria Cell Atlas):

Stage	LR class	MCA mean	MCA prop. zeros
Sporozoite	no data	N/A	N/A
Ring	no data	nd	1.00
Trophozoite	no data	nd	1.00
Schizont	no data	nd	1.00
Gametocyte	no data	nd	1.00

More info:

Resistome Mutations

Old (Pf3D7v3) Gene ID: PF3D7_0300600

Resistome Missense Mutations: None

Resistome Compounds with Missense Mutations: None

Resistome # Samples with Disruptive Mutations: 0 (0 missense, 0 "interesting" missense)

Essentiality (ABS)

Zhang Phenotype: Non - Mutable in CDS *tentative

MIS: 0.128 | MFS: -2.728 | #Insertions: 0

PlasmoGEM Phenotype: N/A

RMgmDB ABS Phenotype: N/A

More info: PhenoPlasm Link

Binding Evidence

AlphaFill Uniprot ID: N/A

"Best" AlphaFill ligand hit: No AlphaFill hits

No associated EC numbers

No evidence of orthology to BindingDB entries

Orthology Information

Ortholog Group (OrthoMCL): OG6_110760

No human ortholog(s)

Genetic Variation

MalariaGEN Pf7 (worldwide samples) # unique SNV/indels:

No passing variants found

PlasmoDB Total SNPs: 39

Non-coding: 0 | Synonymous: 21 | Nonsynonymous: 17 | Stop Codon: 1

Protein Information

Protein Length: 70 | Molecular Weight (kDa): 8.458

UniProt ID(s): Q8I4N8

PDB ID(s): None

Isoelectric Point: 6.21

Protein Domain Annotations:

Source	Family ID	Description
InterPro	N/A	N/A
PFam	N/A	N/A
Superfamily	N/A	N/A