Genome location: Pf3D7_03_v3:67,870..68,761(+)
Genome classification: SubtelomericHypervariable
Product Description: stevor
SignalP Peptide: MNIYYAKMLLFIFLINTLLLS
# Transmembrane Domains: 0
EC Numbers: None
Curated GO (PlasmoDB): None
Expression by stage (LR - Le Roch et al., and MCA - Malaria Cell Atlas):
| Stage | LR class | MCA mean | MCA prop. zeros |
|---|---|---|---|
| Sporozoite | not expressed | N/A | N/A |
| Ring | not expressed | 0.00 | 1.00 |
| Trophozoite | not expressed | 0.01 | 1.00 |
| Schizont | not expressed | 0.00 | 1.00 |
| Gametocyte | not expressed | 0.00 | 1.00 |
More info:
Old (Pf3D7v3) Gene ID: PF3D7_0300900
Resistome Missense Mutations: None
Resistome Compounds with Missense Mutations: None
Resistome # Samples with Disruptive Mutations: 0 (0 missense, 0 "interesting" missense)
Zhang Phenotype: Non - Mutable in CDS
MIS: 0.274 | MFS: -2.663 | #Insertions: 0
PlasmoGEM Phenotype: N/A
RMgmDB ABS Phenotype: N/A
More info: PhenoPlasm Link
AlphaFill Uniprot ID: O97329
"Best" AlphaFill ligand hit: HEM (heme, Local RMSD=0.06) with 4NKY (Global RMSD=17.55)
No associated EC numbersNo evidence of orthology to BindingDB entries
MalariaGEN Pf7 (worldwide samples) # unique SNV/indels:
No passing variants found
PlasmoDB Total SNPs: 57
Non-coding: 12 | Synonymous: 19 | Nonsynonymous: 19 | Stop Codon: 7
Protein Length: 216 | Molecular Weight (kDa): 25.776
UniProt ID(s): O97329
PDB ID(s): None
Isoelectric Point: 10.22
Protein Domain Annotations:
| Source | Family ID | Description |
|---|---|---|
| InterPro | IPR006374 | Variant surface antigen Stevor |
| PFam | PF17410 | Variant surface antigen Stevor |
| Superfamily | N/A | N/A |
| PMID | Title | Authors | DOI/Link |
|---|---|---|---|
| 10448855 | The complete nucleotide sequence of chromosome 3 of Plasmodium falciparum. | Bowman S, Lawson D, ..., Barrell BG | 10.1038/22964 |
| 12368867 | Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13. | Hall N, Pain A, ..., Barrell BG | 10.1038/nature01095 |