PF3D7_0709800

Genome location: Pf3D7_07_v3:437,183..438,431(+)

Genome classification: Core

Function and Localization

Product Description: protein BRAWNIN, putative

SignalP Peptide: N/A

# Transmembrane Domains: 1

EC Numbers: None

Curated GO (PlasmoDB): None

Expression by stage (LR - Le Roch et al., and MCA - Malaria Cell Atlas):

Stage	LR class	MCA mean	MCA prop. zeros
Sporozoite	no data	N/A	N/A
Ring	no data	0.07	0.96
Trophozoite	no data	0.13	0.91
Schizont	no data	0.21	0.86
Gametocyte	no data	0.28	0.83

More info:

Resistome Mutations

Old (Pf3D7v3) Gene ID: PF3D7_0709800

Resistome Missense Mutations: None

Resistome Compounds with Missense Mutations: None

Resistome # Samples with Disruptive Mutations: 0 (0 missense, 0 "interesting" missense)

Essentiality (ABS)

Zhang Phenotype: Non - Mutable in CDS *tentative

MIS: 0.331 | MFS: -2.348 | #Insertions: 0

PlasmoGEM Phenotype: N/A

RMgmDB ABS Phenotype: N/A

More info: PhenoPlasm Link

Binding Evidence

AlphaFill Uniprot ID: C0H4M4

"Best" AlphaFill ligand hit: No AlphaFill hits

No associated EC numbers

No evidence of orthology to BindingDB entries

Orthology Information

Ortholog Group (OrthoMCL): OG6_533655

No human ortholog(s)

Genetic Variation

MalariaGEN Pf7 (worldwide samples) # unique SNV/indels:

No passing variants found

PlasmoDB Total SNPs: 119

Non-coding: 113 | Synonymous: 5 | Nonsynonymous: 1 | Stop Codon: 0

Protein Information

Protein Length: 64 | Molecular Weight (kDa): 7.351

UniProt ID(s): C0H4M4

PDB ID(s): None

Isoelectric Point: 8.77

Protein Domain Annotations:

Source	Family ID	Description
InterPro	IPR027858	Protein BRAWNIN
PFam	PF14990	Protein BRAWNIN
Superfamily	N/A	N/A