Product Description: ATP synthase F0 subunit a-like protein, putative
SignalP Peptide: N/A
# Transmembrane Domains: 2
EC Numbers: None
Curated GO (PlasmoDB):
Type | GO Term | Name |
---|---|---|
Component | GO:0005739 | mitochondrion |
Expression by stage (LR - Le Roch et al., and MCA - Malaria Cell Atlas):
Stage | LR class | MCA mean | MCA prop. zeros |
---|---|---|---|
Sporozoite | expressed | N/A | N/A |
Ring | possibly expressed | 0.04 | 0.98 |
Trophozoite | expressed | 0.43 | 0.74 |
Schizont | expressed | 0.21 | 0.86 |
Gametocyte | expressed | 1.03 | 0.49 |
More info:
Old (Pf3D7v3) Gene ID: PF3D7_0719100
Resistome Missense Mutations: None
Resistome Compounds with Missense Mutations: None
Resistome # Samples with Disruptive Mutations: 0 (0 missense, 0 "interesting" missense)
Zhang Phenotype: Non - Mutable in CDS
MIS: 0.143 | MFS: -3.6 | #Insertions: 0
PlasmoGEM Phenotype: N/A
RMgmDB ABS Phenotype: N/A
More info: PhenoPlasm Link
AlphaFill Uniprot ID: Q8IBR0
"Best" AlphaFill ligand hit: No AlphaFill hits
No associated EC numbersNo evidence of orthology to BindingDB entries
MalariaGEN Pf7 (worldwide samples) # unique SNV/indels:
Homozygous genotype calls only
variant type | common | rare | doubleton | singleton |
---|---|---|---|---|
synonymous | 2 | 9 | 7 | 16 |
disruptive | 1 | 10 | 4 | 16 |
missense | 1 | 9 | 4 | 14 |
Any inclusion in genotype call
variant type | common | rare | doubleton | singleton |
---|---|---|---|---|
synonymous | 3 | 16 | 13 | 10 |
disruptive | 4 | 24 | 12 | 22 |
missense | 1 | 20 | 9 | 18 |
PlasmoDB Total SNPs: 132
Non-coding: 124 | Synonymous: 5 | Nonsynonymous: 3 | Stop Codon: 0
Protein Length: 179 | Molecular Weight (kDa): 21.33
UniProt ID(s): Q8IBR0
PDB ID(s): None
Isoelectric Point: 9.91
Protein Domain Annotations:
Source | Family ID | Description |
---|---|---|
InterPro | N/A | N/A |
PFam | N/A | N/A |
Superfamily | N/A | N/A |
PMID | Title | Authors | DOI/Link |
---|---|---|---|
34494883 | A Prioritized and Validated Resource of Mitochondrial Proteins in PlasmodiumIdentifies Unique Biology. | van Esveld SL, Meerstein-Kessel L, ..., Huynen MA | 10.1128/mSphere.00614-21 |