PF3D7_0726050

Genome location: Pf3D7_07_v3:1,092,439..1,092,741(-)

Genome classification: Core

Function and Localization

Product Description: conserved Plasmodium protein, unknown function

SignalP Peptide: MHIIKIFILVITTFLINNLFES

# Transmembrane Domains: 1

EC Numbers: None

Curated GO (PlasmoDB): None

Expression by stage (LR - Le Roch et al., and MCA - Malaria Cell Atlas):

Stage	LR class	MCA mean	MCA prop. zeros
Sporozoite	no data	N/A	N/A
Ring	no data	nd	nd
Trophozoite	no data	nd	nd
Schizont	no data	nd	nd
Gametocyte	no data	nd	nd

More info:

Resistome Mutations

No corresponding Pf3D7v3 gene ID in resistome database

Essentiality (ABS)

Zhang Phenotype: N/A

PlasmoGEM Phenotype: N/A

RMgmDB ABS Phenotype: N/A

More info: PhenoPlasm Link

Binding Evidence

AlphaFill Uniprot ID: A0A5K1K8M1

"Best" AlphaFill ligand hit: No AlphaFill hits

No associated EC numbers

No evidence of orthology to BindingDB entries

Orthology Information

Ortholog Group (OrthoMCL): OG6r19_109673

No human ortholog(s)

Genetic Variation

MalariaGEN Pf7 (worldwide samples) # unique SNV/indels:

Homozygous genotype calls only

variant type	common	rare	doubleton	singleton
synonymous	0	12	10	4
disruptive	9	62	28	39
missense	4	42	13	20

Any inclusion in genotype call

variant type	common	rare	doubleton	singleton
synonymous	1	25	1	1
disruptive	23	107	32	46
missense	14	60	15	21

PlasmoDB Total SNPs: 20

Non-coding: 0 | Synonymous: 8 | Nonsynonymous: 12 | Stop Codon: 0

Protein Information

Protein Length: 100 | Molecular Weight (kDa): 11.62

UniProt ID(s): A0A5K1K8M1

PDB ID(s): None

Isoelectric Point: 10.54

Protein Domain Annotations:

Source	Family ID	Description
InterPro	N/A	N/A
PFam	N/A	N/A
Superfamily	N/A	N/A