Genome location: Pf3D7_07_v3:1,258,496..1,260,113(+)
Genome classification: Core
Product Description: COX assembly mitochondrial protein, putative
SignalP Peptide: N/A
# Transmembrane Domains: 0
EC Numbers: None
Curated GO (PlasmoDB):
Type | GO Term | Name |
---|---|---|
Component | GO:0005739 | mitochondrion |
Expression by stage (LR - Le Roch et al., and MCA - Malaria Cell Atlas):
Stage | LR class | MCA mean | MCA prop. zeros |
---|---|---|---|
Sporozoite | not expressed | N/A | N/A |
Ring | not expressed | nd | nd |
Trophozoite | not expressed | nd | nd |
Schizont | expressed | nd | nd |
Gametocyte | possibly expressed | nd | nd |
More info:
Old (Pf3D7v3) Gene ID: PF3D7_0729600
Resistome Missense Mutations: None
Resistome Compounds with Missense Mutations: None
Resistome # Samples with Disruptive Mutations: 0 (0 missense, 0 "interesting" missense)
Zhang Phenotype: Non - Mutable in CDS *tentative
MIS: 0.989 | MFS: 0 | #Insertions: 0
PlasmoGEM Phenotype: N/A
RMgmDB ABS Phenotype: N/A
More info: PhenoPlasm Link
AlphaFill Uniprot ID: A0A143ZXB4
"Best" AlphaFill ligand hit: No AlphaFill hits
No associated EC numbersNo evidence of orthology to BindingDB entries
MalariaGEN Pf7 (worldwide samples) # unique SNV/indels:
Homozygous genotype calls only
variant type | common | rare | doubleton | singleton |
---|---|---|---|---|
synonymous | 2 | 8 | 4 | 13 |
disruptive | 0 | 14 | 5 | 13 |
missense | 0 | 12 | 5 | 12 |
Any inclusion in genotype call
variant type | common | rare | doubleton | singleton |
---|---|---|---|---|
synonymous | 4 | 15 | 8 | 11 |
disruptive | 3 | 26 | 8 | 35 |
missense | 1 | 20 | 7 | 25 |
PlasmoDB Total SNPs: 76
Non-coding: 68 | Synonymous: 8 | Nonsynonymous: 0 | Stop Codon: 0
Protein Length: 163 | Molecular Weight (kDa): 20.13
UniProt ID(s): A0A143ZXB4
PDB ID(s): None
Isoelectric Point: 9.81
Protein Domain Annotations:
Source | Family ID | Description |
---|---|---|
InterPro | IPR013892 | Cytochrome c oxidase biogenesis protein Cmc1-like |
PFam | PF08583 | Cytochrome c oxidase biogenesis protein Cmc1-like |
Superfamily | N/A | N/A |
No associated publications