Product Description: ubiquitin-like protein, putative
SignalP Peptide: N/A
# Transmembrane Domains: 0
EC Numbers: None
Curated GO (PlasmoDB):
Type | GO Term | Name |
---|---|---|
Component | GO:0005634 | nucleus |
Expression by stage (LR - Le Roch et al., and MCA - Malaria Cell Atlas):
Stage | LR class | MCA mean | MCA prop. zeros |
---|---|---|---|
Sporozoite | possibly expressed | N/A | N/A |
Ring | expressed | 0.09 | 0.95 |
Trophozoite | expressed | 0.40 | 0.75 |
Schizont | expressed | 0.93 | 0.51 |
Gametocyte | expressed | 0.67 | 0.65 |
More info:
Old (Pf3D7v3) Gene ID: PF3D7_0819600
Resistome Missense Mutations: None
Resistome Compounds with Missense Mutations: None
Resistome # Samples with Disruptive Mutations: 0 (0 missense, 0 "interesting" missense)
Zhang Phenotype: Non - Mutable in CDS
MIS: 0.123 | MFS: -3.082 | #Insertions: 0
PlasmoGEM Phenotype: Dispensable (Pb ortholog: PBANKA_0711200)
RMgmDB ABS Phenotype: Different from wild type (Pb ortholog: PBANKA_0711200)
Modification: Disrupted | RMgm-2221
More info: PhenoPlasm Link
AlphaFill Uniprot ID: Q8IB31
"Best" AlphaFill ligand hit: No AlphaFill hits
No associated EC numbersNo evidence of orthology to BindingDB entries
MalariaGEN Pf7 (worldwide samples) # unique SNV/indels:
Homozygous genotype calls only
variant type | common | rare | doubleton | singleton |
---|---|---|---|---|
synonymous | 0 | 0 | 0 | 0 |
disruptive | 0 | 0 | 0 | 0 |
missense | 0 | 0 | 0 | 0 |
Any inclusion in genotype call
variant type | common | rare | doubleton | singleton |
---|---|---|---|---|
synonymous | 0 | 0 | 0 | 0 |
disruptive | 0 | 0 | 0 | 1 |
missense | 0 | 0 | 0 | 0 |
PlasmoDB Total SNPs: 206
Non-coding: 178 | Synonymous: 19 | Nonsynonymous: 9 | Stop Codon: 0
Protein Length: 277 | Molecular Weight (kDa): 32.165
UniProt ID(s): Q8IB31
PDB ID(s): None
Isoelectric Point: 4.93
Protein Domain Annotations:
Source | Family ID | Description |
---|---|---|
InterPro | IPR000626 | Ubiquitin-like domain |
InterPro | IPR029071 | Ubiquitin-like domain superfamily |
PFam | PF00240 | Ubiquitin-like domain |
Superfamily | SSF54236 | Ubiquitin-like domain superfamily |
PMID | Title | Authors | DOI/Link |
---|---|---|---|
23181666 | Organellar proteomics reveals hundreds of novel nuclear proteins in the malariaparasite Plasmodium falciparum. | Oehring SC, Woodcroft BJ, ..., Voss TS | 10.1186/gb-2012-13-11-r108 |