Genome location: Pf3D7_08_v3:1,426,884..1,428,135(+)
Genome classification: SubtelomericHypervariable
Product Description: rifin
SignalP Peptide: MKLHYTKILLICLPLNILVLS
# Transmembrane Domains: 1
EC Numbers: None
Curated GO (PlasmoDB): None
Expression by stage (LR - Le Roch et al., and MCA - Malaria Cell Atlas):
| Stage | LR class | MCA mean | MCA prop. zeros |
|---|---|---|---|
| Sporozoite | no data | N/A | N/A |
| Ring | no data | 0.00 | 1.00 |
| Trophozoite | no data | 0.00 | 1.00 |
| Schizont | no data | nd | 1.00 |
| Gametocyte | no data | 0.00 | 1.00 |
More info:
Old (Pf3D7v3) Gene ID: PF3D7_0833200
Resistome Missense Mutations: N345D, A348T
Resistome Compounds with Missense Mutations: Halofuginone
Resistome # Samples with Disruptive Mutations: 1 (1 missense, 0 "interesting" missense)
Zhang Phenotype: Non - Mutable in CDS *tentative
MIS: 0.522 | MFS: 0 | #Insertions: 0
PlasmoGEM Phenotype: N/A
RMgmDB ABS Phenotype: N/A
More info: PhenoPlasm Link
AlphaFill Uniprot ID: A0A143ZWV2
"Best" AlphaFill ligand hit: No AlphaFill hits
No associated EC numbersNo evidence of orthology to BindingDB entries
MalariaGEN Pf7 (worldwide samples) # unique SNV/indels:
No passing variants found
PlasmoDB Total SNPs: 495
Non-coding: 83 | Synonymous: 103 | Nonsynonymous: 302 | Stop Codon: 7
Protein Length: 356 | Molecular Weight (kDa): 39.744
UniProt ID(s): A0A143ZWV2
PDB ID(s): None
Isoelectric Point: 9.94
Protein Domain Annotations:
| Source | Family ID | Description |
|---|---|---|
| InterPro | IPR006373 | Variant surface antigen Rifin |
| PFam | PF02009 | Variant surface antigen Rifin |
| Superfamily | N/A | N/A |
No associated publications