About Gene List

PF3D7_0901200

Genome location: Pf3D7_09_v3:64,216..64,428(-)

Genome classification: SubtelomericHypervariable

Function and Localization

Product Description: Plasmodium exported protein, unknown function, fragment

SignalP Peptide: N/A

# Transmembrane Domains: 0

EC Numbers: None

Curated GO (PlasmoDB): None

Expression by stage (LR - Le Roch et al., and MCA - Malaria Cell Atlas):

Stage LR class MCA mean MCA prop. zeros
Sporozoite not expressed N/A N/A
Ring possibly expressed nd 1.00
Trophozoite possibly expressed nd 1.00
Schizont possibly expressed nd 1.00
Gametocyte possibly expressed nd 1.00

More info:

Resistome Mutations

Old (Pf3D7v3) Gene ID: PF3D7_0901200

Resistome Missense Mutations: None

Resistome Compounds with Missense Mutations: None

Resistome # Samples with Disruptive Mutations: 0 (0 missense, 0 "interesting" missense)

Essentiality (ABS)

Zhang Phenotype: Mutable in CDS

MIS: 0.934 | MFS: -2.728 | #Insertions: 1

PlasmoGEM Phenotype: N/A

RMgmDB ABS Phenotype: N/A

More info: PhenoPlasm Link

Binding Evidence

AlphaFill Uniprot ID: N/A

"Best" AlphaFill ligand hit: No AlphaFill hits

No associated EC numbers

No evidence of orthology to BindingDB entries

Orthology Information

Ortholog Group (OrthoMCL): OG6_110760

No human ortholog(s)

Genetic Variation

MalariaGEN Pf7 (worldwide samples) # unique SNV/indels:

No passing variants found

PlasmoDB Total SNPs: 57

Non-coding: 0 | Synonymous: 17 | Nonsynonymous: 40 | Stop Codon: 0

Protein Information

Protein Length: 70 | Molecular Weight (kDa): 8.442

UniProt ID(s): None

PDB ID(s): None

Isoelectric Point: 7.16

Protein Domain Annotations:

Source Family ID Description
InterPro N/A N/A
PFam N/A N/A
Superfamily N/A N/A

Associated Publications

PMID Title Authors DOI/Link
12368867 Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13. Hall N, Pain A, ..., Barrell BG 10.1038/nature01095