PF3D7_0907000

Genome location: Pf3D7_09_v3:337,190..338,027(+)

Genome classification: Core

Function and Localization

Product Description: conserved Plasmodium protein, unknown function

SignalP Peptide: N/A

# Transmembrane Domains: 0

EC Numbers: None

Curated GO (PlasmoDB): None

Expression by stage (LR - Le Roch et al., and MCA - Malaria Cell Atlas):

Stage	LR class	MCA mean	MCA prop. zeros
Sporozoite	no data	N/A	N/A
Ring	no data	0.48	0.77
Trophozoite	no data	0.47	0.72
Schizont	no data	0.22	0.86
Gametocyte	no data	0.33	0.80

More info:

Resistome Mutations

Old (Pf3D7v3) Gene ID: PF3D7_0907000

Resistome Missense Mutations: None

Resistome Compounds with Missense Mutations: None

Resistome # Samples with Disruptive Mutations: 0 (0 missense, 0 "interesting" missense)

Essentiality (ABS)

Zhang Phenotype: Non - Mutable in CDS *tentative

MIS: 0.385 | MFS: -3.279 | #Insertions: 0

PlasmoGEM Phenotype: N/A

RMgmDB ABS Phenotype: N/A

More info: PhenoPlasm Link

Binding Evidence

AlphaFill Uniprot ID: C0H523

"Best" AlphaFill ligand hit: No AlphaFill hits

No associated EC numbers

No evidence of orthology to BindingDB entries

Orthology Information

Ortholog Group (OrthoMCL): OG6_533200

No human ortholog(s)

Genetic Variation

MalariaGEN Pf7 (worldwide samples) # unique SNV/indels:

Homozygous genotype calls only

variant type	common	rare	doubleton	singleton
synonymous	1	9	2	5
disruptive	1	9	4	16
missense	1	8	4	10

Any inclusion in genotype call

variant type	common	rare	doubleton	singleton
synonymous	1	14	3	6
disruptive	3	21	8	22
missense	1	19	5	14

PlasmoDB Total SNPs: 40

Non-coding: 33 | Synonymous: 7 | Nonsynonymous: 0 | Stop Codon: 0

Protein Information

Protein Length: 80 | Molecular Weight (kDa): 9.501

UniProt ID(s): C0H523

PDB ID(s): None

Isoelectric Point: 4.29

Protein Domain Annotations:

Source	Family ID	Description
InterPro	N/A	N/A
PFam	N/A	N/A
Superfamily	N/A	N/A