Product Description: conserved Plasmodium protein, unknown function
SignalP Peptide: N/A
# Transmembrane Domains: 1
EC Numbers: None
Curated GO (PlasmoDB):
| Type | GO Term | Name |
|---|---|---|
| Component | GO:0009986 | cell surface |
Expression by stage (LR - Le Roch et al., and MCA - Malaria Cell Atlas):
| Stage | LR class | MCA mean | MCA prop. zeros |
|---|---|---|---|
| Sporozoite | no data | N/A | N/A |
| Ring | no data | 0.46 | 0.80 |
| Trophozoite | no data | 0.59 | 0.66 |
| Schizont | no data | 0.28 | 0.84 |
| Gametocyte | no data | 0.42 | 0.76 |
More info:
Old (Pf3D7v3) Gene ID: PF3D7_0926200
Resistome Missense Mutations: None
Resistome Compounds with Missense Mutations: None
Resistome # Samples with Disruptive Mutations: 0 (0 missense, 0 "interesting" missense)
Zhang Phenotype: Non - Mutable in CDS *tentative
MIS: 0.153 | MFS: 0 | #Insertions: 0
PlasmoGEM Phenotype: Essential (Pb ortholog: PBANKA_0827000)
RMgmDB ABS Phenotype: Different from wild type (Pb ortholog: PBANKA_0827000)
Modification: Tagged | RMgm-4530
More info: PhenoPlasm Link
AlphaFill Uniprot ID: C0H562
"Best" AlphaFill ligand hit: No AlphaFill hits
No associated EC numbersNo evidence of orthology to BindingDB entries
MalariaGEN Pf7 (worldwide samples) # unique SNV/indels:
No passing variants found
PlasmoDB Total SNPs: 124
Non-coding: 122 | Synonymous: 2 | Nonsynonymous: 0 | Stop Codon: 0
Protein Length: 51 | Molecular Weight (kDa): 5.849
UniProt ID(s): C0H562
PDB ID(s): None
Isoelectric Point: 7.79
Protein Domain Annotations:
| Source | Family ID | Description |
|---|---|---|
| InterPro | N/A | N/A |
| PFam | N/A | N/A |
| Superfamily | N/A | N/A |
| PMID | Title | Authors | DOI/Link |
|---|---|---|---|
| 12368867 | Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13. | Hall N, Pain A, ..., Barrell BG | 10.1038/nature01095 |
| 30232409 | An in silico down-scaling approach uncovers novel constituents of thePlasmodium-containing vacuole. | Matz JM, Matuschewski K | 10.1038/s41598-018-32471-6 |