PF3D7_0929800

Genome location: Pf3D7_09_v3:1,186,606..1,186,902(-)

Genome classification: Core

Function and Localization

Product Description: conserved Plasmodium protein, unknown function

SignalP Peptide: N/A

# Transmembrane Domains: 1

EC Numbers: None

Curated GO (PlasmoDB): None

Expression by stage (LR - Le Roch et al., and MCA - Malaria Cell Atlas):

Stage	LR class	MCA mean	MCA prop. zeros
Sporozoite	not expressed	N/A	N/A
Ring	not expressed	0.03	0.99
Trophozoite	not expressed	0.34	0.79
Schizont	expressed	0.11	0.92
Gametocyte	not expressed	0.12	0.92

More info:

Resistome Mutations

Old (Pf3D7v3) Gene ID: PF3D7_0929800

Resistome Missense Mutations: None

Resistome Compounds with Missense Mutations: None

Resistome # Samples with Disruptive Mutations: 0 (0 missense, 0 "interesting" missense)

Essentiality (ABS)

Zhang Phenotype: Non - Mutable in CDS *tentative

MIS: 0.18 | MFS: -3.295 | #Insertions: 0

PlasmoGEM Phenotype: N/A

RMgmDB ABS Phenotype: N/A

More info: PhenoPlasm Link

Binding Evidence

AlphaFill Uniprot ID: C0H573

"Best" AlphaFill ligand hit: No AlphaFill hits

No associated EC numbers

No evidence of orthology to BindingDB entries

Orthology Information

Ortholog Group (OrthoMCL): OG6_149553

No human ortholog(s)

Genetic Variation

MalariaGEN Pf7 (worldwide samples) # unique SNV/indels:

Homozygous genotype calls only

variant type	common	rare	doubleton	singleton
synonymous	0	2	1	4
disruptive	1	1	5	6
missense	1	1	5	6

Any inclusion in genotype call

variant type	common	rare	doubleton	singleton
synonymous	1	2	3	6
disruptive	3	8	7	12
missense	2	7	5	9

PlasmoDB Total SNPs: 3

Non-coding: 0 | Synonymous: 1 | Nonsynonymous: 2 | Stop Codon: 0

Protein Information

Protein Length: 98 | Molecular Weight (kDa): 11.876

UniProt ID(s): C0H573

PDB ID(s): None

Isoelectric Point: 10.28

Protein Domain Annotations:

Source	Family ID	Description
InterPro	N/A	N/A
PFam	N/A	N/A
Superfamily	N/A	N/A