About Gene List

PF3D7_1302050

Genome location: Pf3D7_13_v3:118,901..119,247(+)

Genome classification: Core

Function and Localization

Product Description: hypothetical protein

SignalP Peptide: N/A

# Transmembrane Domains: 1

EC Numbers: None

Curated GO (PlasmoDB): None

Expression by stage (LR - Le Roch et al., and MCA - Malaria Cell Atlas):

Stage LR class MCA mean MCA prop. zeros
Sporozoite no data N/A N/A
Ring no data nd nd
Trophozoite no data nd nd
Schizont no data nd nd
Gametocyte no data nd nd

More info:

Resistome Mutations

No corresponding Pf3D7v3 gene ID in resistome database

Essentiality (ABS)

Zhang Phenotype: N/A

PlasmoGEM Phenotype: N/A

RMgmDB ABS Phenotype: N/A

More info: PhenoPlasm Link

Binding Evidence

AlphaFill Uniprot ID: A0A5K1K810

"Best" AlphaFill ligand hit: No AlphaFill hits

No associated EC numbers

No evidence of orthology to BindingDB entries

Orthology Information

Ortholog Group (OrthoMCL): OG6r19_109672

No human ortholog(s)

Genetic Variation

MalariaGEN Pf7 (worldwide samples) # unique SNV/indels:

Homozygous genotype calls only

variant type common rare doubleton singleton
synonymous 0 2 1 2
disruptive 4 15 9 14
missense 3 14 7 10

Any inclusion in genotype call

variant type common rare doubleton singleton
synonymous 0 3 4 3
disruptive 9 26 16 27
missense 7 22 12 12

PlasmoDB Total SNPs: 36

Non-coding: 32 | Synonymous: 2 | Nonsynonymous: 2 | Stop Codon: 0

Protein Information

Protein Length: 80 | Molecular Weight (kDa): 9.734

UniProt ID(s): A0A5K1K810

PDB ID(s): None

Isoelectric Point: 8.32

Protein Domain Annotations:

Source Family ID Description
InterPro N/A N/A
PFam N/A N/A
Superfamily N/A N/A

Associated Publications

No associated publications