Product Description: apical ring associated protein 1, putative
SignalP Peptide: N/A
# Transmembrane Domains: 0
EC Numbers: None
Curated GO (PlasmoDB):
Type | GO Term | Name |
---|---|---|
Component | GO:0020031 | polar ring of apical complex |
Expression by stage (LR - Le Roch et al., and MCA - Malaria Cell Atlas):
Stage | LR class | MCA mean | MCA prop. zeros |
---|---|---|---|
Sporozoite | no data | N/A | N/A |
Ring | no data | 0.01 | 0.99 |
Trophozoite | no data | 0.00 | 1.00 |
Schizont | no data | 0.01 | 0.99 |
Gametocyte | no data | 0.11 | 0.93 |
More info:
No corresponding Pf3D7v3 gene ID in resistome database
Zhang Phenotype: N/A
PlasmoGEM Phenotype: N/A
RMgmDB ABS Phenotype: Not tested (Pb ortholog: PY17X_1412750)
Modification: Disrupted | RMgm-5287
More info: PhenoPlasm Link
AlphaFill Uniprot ID: A0A146M158
"Best" AlphaFill ligand hit: No AlphaFill hits
No associated EC numbersNo evidence of orthology to BindingDB entries
MalariaGEN Pf7 (worldwide samples) # unique SNV/indels:
Homozygous genotype calls only
variant type | common | rare | doubleton | singleton |
---|---|---|---|---|
synonymous | 2 | 2 | 6 | 7 |
disruptive | 8 | 16 | 3 | 6 |
missense | 8 | 16 | 3 | 6 |
Any inclusion in genotype call
variant type | common | rare | doubleton | singleton |
---|---|---|---|---|
synonymous | 2 | 13 | 4 | 5 |
disruptive | 12 | 19 | 8 | 13 |
missense | 12 | 17 | 7 | 11 |
PlasmoDB Total SNPs: 10
Non-coding: 0 | Synonymous: 2 | Nonsynonymous: 8 | Stop Codon: 0
Protein Length: 63 | Molecular Weight (kDa): 6.834
UniProt ID(s): A0A146M158
PDB ID(s): None
Isoelectric Point: 9.73
Protein Domain Annotations:
Source | Family ID | Description |
---|---|---|
InterPro | N/A | N/A |
PFam | N/A | N/A |
Superfamily | N/A | N/A |
PMID | Title | Authors | DOI/Link |
---|---|---|---|
26018192 | Genome-Wide Identification of the Target Genes of AP2-O, a Plasmodium AP2-FamilyTranscription Factor. | Kaneko I, Iwanaga S, ..., Yuda M | 10.1371/journal.ppat.1004905 |
33845171 | High-yield production of (R)-acetoin in Saccharomyces cerevisiae by deletinggenes for NAD(P)H-dependent ketone reductases producing meso-2,3-butanediol and2,3-dimethylglycerate | Bae SJ, Kim S, ..., Hahn JS | 10.1016/j.ymben.2021.04.001 |
37449952 | Understanding the role of GRE3 in the erythritol biosynthesis pathway inSaccharomyces uvarum and its implication in osmoregulation and redox homeostasis | Albillos-Arenal S, Minebois R, Querol A, Barrio E | 10.1111/1751-7915.14313 |
27400981 | alpha,beta-Dicarbonyl reduction is mediated by the Saccharomyces Old Yellow Enzyme | van Bergen B, Cyr N, ..., Jardim A | 10.1093/femsyr/fow059 |