PF3D7_1470300

Genome location: Pf3D7_14_v3:2,879,219..2,880,783(+)

Genome classification: Core

Function and Localization

Product Description: conserved Plasmodium protein, unknown function

SignalP Peptide: N/A

# Transmembrane Domains: 0

EC Numbers: None

Curated GO (PlasmoDB): None

Expression by stage (LR - Le Roch et al., and MCA - Malaria Cell Atlas):

Stage	LR class	MCA mean	MCA prop. zeros
Sporozoite	not expressed	N/A	N/A
Ring	possibly expressed	0.86	0.62
Trophozoite	possibly expressed	0.46	0.74
Schizont	not expressed	0.11	0.94
Gametocyte	not expressed	1.03	0.48

More info:

Resistome Mutations

Old (Pf3D7v3) Gene ID: PF3D7_1470300

Resistome Missense Mutations: None

Resistome Compounds with Missense Mutations: None

Resistome # Samples with Disruptive Mutations: 0 (0 missense, 0 "interesting" missense)

Essentiality (ABS)

Zhang Phenotype: Non - Mutable in CDS *tentative

MIS: 0.134 | MFS: -3.148 | #Insertions: 0

PlasmoGEM Phenotype: N/A

RMgmDB ABS Phenotype: N/A

More info: PhenoPlasm Link

Binding Evidence

AlphaFill Uniprot ID: Q8IKD5

"Best" AlphaFill ligand hit: No AlphaFill hits

No associated EC numbers

No evidence of orthology to BindingDB entries

Orthology Information

Ortholog Group (OrthoMCL): OG6_533039

No human ortholog(s)

Genetic Variation

MalariaGEN Pf7 (worldwide samples) # unique SNV/indels:

No passing variants found

PlasmoDB Total SNPs: 89

Non-coding: 78 | Synonymous: 4 | Nonsynonymous: 7 | Stop Codon: 0

Protein Information

Protein Length: 148 | Molecular Weight (kDa): 18.248

UniProt ID(s): Q8IKD5

PDB ID(s): None

Isoelectric Point: 10.96

Protein Domain Annotations:

Source	Family ID	Description
InterPro	N/A	N/A
PFam	N/A	N/A
Superfamily	N/A	N/A