About Gene List

PF3D7_1470950

Genome location: Pf3D7_14_v3:2,899,811..2,900,086(-)

Genome classification: Core

Function and Localization

Product Description: small integral membrane protein 15, putative

SignalP Peptide: N/A

# Transmembrane Domains: 2

EC Numbers: None

Curated GO (PlasmoDB): None

Expression by stage (LR - Le Roch et al., and MCA - Malaria Cell Atlas):

Stage LR class MCA mean MCA prop. zeros
Sporozoite no data N/A N/A
Ring no data nd nd
Trophozoite no data nd nd
Schizont no data nd nd
Gametocyte no data nd nd

More info:

Resistome Mutations

No corresponding Pf3D7v3 gene ID in resistome database

Essentiality (ABS)

Zhang Phenotype: N/A

PlasmoGEM Phenotype: N/A

RMgmDB ABS Phenotype: N/A

More info: PhenoPlasm Link

Binding Evidence

AlphaFill Uniprot ID: N/A

"Best" AlphaFill ligand hit: No AlphaFill hits

No associated EC numbers

No evidence of orthology to BindingDB entries

Orthology Information

Ortholog Group (OrthoMCL): OG6r19_195766

No human ortholog(s)

Genetic Variation

MalariaGEN Pf7 (worldwide samples) # unique SNV/indels:

No passing variants found

PlasmoDB Total SNPs: 3

Non-coding: 0 | Synonymous: 2 | Nonsynonymous: 1 | Stop Codon: 0

Protein Information

Protein Length: 91 | Molecular Weight (kDa): 11.078

UniProt ID(s): None

PDB ID(s): None

Isoelectric Point: 9.85

Protein Domain Annotations:

Source Family ID Description
InterPro IPR027877 Small integral membrane protein 15
PFam PF15086 Small integral membrane protein 15
Superfamily N/A N/A

Associated Publications

No associated publications